Antigen-specific immunotherapies for acute myeloid leukemia
نویسندگان
چکیده
منابع مشابه
Antigen-specific immunotherapies for acute myeloid leukemia.
Antigen-specific immunotherapies have emerged as important components of curative treatment algorithms for many cancers. In acute myeloid leukemia (AML), success has been less obvious. Nonetheless, among the few drugs shown to improve survival in recent randomized trials is the CD33 antibody-drug conjugate gemtuzumab ozogamicin. Significant antileukemic activity is also well documented for radi...
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Relapse after chemotherapy is inevitable in the majority of patients with acute myeloid leukemia (AML). Thus, it is necessary to develop novel therapies that have different antileukemic mechanisms. Recent advances in immunology and identification of promising leukemia-associated antigens open the possibilities for eradicating minimal residual diseases by antigen-specific immunotherapy after che...
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ژورنال
عنوان ژورنال: Hematology
سال: 2015
ISSN: 1520-4391,1520-4383
DOI: 10.1182/asheducation-2015.1.584